When they are born, they are barely visible spots, And,
Daniel 7:6 talks of a leopard, Daniel 7 in general talks about a turbulent sea of nations and that 4 nations rise out of that stormy sea of nations. The storm could easily be the 2 world wars we had, nearly back to back. The first beast could be the nations Britain and the US (the lion and eagle combined), the second beast could be what was the bear USSR, gobbling up the many smaller nations around it, the 3rd could be China, for the tiger and the dragon represent her throughout her history (tiger/leopard are very close and the tiger/dragon combined would be much like the 3rd beast. With much of the 3rd beast transformed, you might not see the spots, plus Leopards were native to Cush, and rarely seen in Egypt much less by the Euphrates where Daniel lived.) This is what I thought when I read your question, not sure that it applies....